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Global Update on COVID19 Vaccine and Treatment

Race to develop COVID19 vaccine is on! 

The purpose of this thread is to monitor the status of all covid19 vaccines being developed worldwide. 
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Comments

  • tambayan102tambayan102 PEx Veteran ⭐⭐
    1. Moderna Inc.
    2. Johnson & Johnson
    3. Sanofi
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    4. Pfizer + Germany's BioNtech
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    5. Britain's AstraZeneca + University of Oxford 

    6.Novavax

    7. Bern's Inselspital hospital in Switzerland.
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    1. Moderna Inc + Swiss contract drugmaker Lonza Group AG
    - ongoing phase 1
    - phase 2 @ 2nd quarter
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    "Pfizer and the German pharmaceutical company BioNTech announced that their potential coronavirus vaccine began human trials in the United States on Monday. If the tests are successful, the vaccine could be ready for emergency use here as early as September."
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    Phase 1 of human trial test the vaccine in HUNDREDS of healthy volunteers.

    Phase 2  of human trial test the vaccine in THOUSANDS of healthy volunteers.
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    edited May 5
    Vaccine Update as of 1st week of May

    1. Pfizer + Germany's BioNtech
    STATUS : ongoing human trial (phase 1)

    2. Moderna Inc + Swiss Lonza Group AG
    STATUS : ongoing human trial (phase 1)

    3. French Sanofi SA + British GlaxoSmithKline Plc
    STATUS : human trial P1 scheduled @ September
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    edited May 6
    Phase 1 of human trial test the vaccine in HUNDREDS of healthy volunteers.

    Phase 2  of human trial test the vaccine in THOUSANDS of healthy volunteers.
    Correction:

    Phase 1 @ 20-100
    Phase 2 @ 101-300
    Phase 3 @ 301-3000
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    edited May 6
    "Phase II clinical programs historically have experienced the lowest success rate of the four development phases.

    In 2010, the percentage of phase II trials that proceeded to phase III was 18%

    And only 30.7% of developmental candidates advanced from Phase II to Phase III in a large study of trials from 2006–2015."

  • tambayan102tambayan102 PEx Veteran ⭐⭐
    edited May 6
    Phase lll success rate

    "As of 2010, about 50% of drug candidates either fail during the Phase III trial or are rejected by the national regulatory agency."
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    US immunotherapy company Inovio Pharmaceuticals Inc
    - animal trial (done)
    - human trial Phase 1 (results by June)
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    "Inovio's vaccine was designed using its DNA medicine platform, while Moderna's vaccine uses messenger RNA (mRNA) technology. Both companies have no approved drug in the market."

  • tambayan102tambayan102 PEx Veteran ⭐⭐
    "Inovio's vaccine efforts are funded by a global coalition"
  • BrwinwaBrwinwa PEx Rookie ⭐
    I hope vaccine can be ready ASAP. and it shouldn't be too expensive.
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    edited June 5
    1. Britain's AstraZeneca + University of Oxford 
    - human, Phase 1 and 2 (done last April)
    - human P3 (ongoing, data by August)
    - target roll out by September

    2. Pfizer + Germany's BioNtech
    - human trial Phase 1 (ongoing)

    3. Moderna Inc + Swiss Lonza Group AG
    -  human trial Phase 1 (done)
    -  human trial P2 (Quarter 2)
    -  human trial P3 (July)

    4. US immunotherapy company Inovio Pharmaceuticals Inc
    - human trial Phase 1 (results by June)

    5. French Sanofi SA + British GlaxoSmithKline Plc
    - human trial Phase 1 (by Sep)

  • tambayan102tambayan102 PEx Veteran ⭐⭐
    We might see a covid19 vaccine or treatment by late Septemper or early October. Then sunod sunod na ang ibang brand ng mga vaccine/treatment. The world needs not just 1, 2 or 3 vaccines but several vaccines. We hope most of the vaccines currently ongoing trial will be successful.
  • Plantation BoyPlantation Boy PEx Influencer ⭐⭐⭐
    So far, none....
  • tambayan102tambayan102 PEx Veteran ⭐⭐
    So far, none....
    Safety first. Vaccine still has to undergo 3 phases of human clinical trial to make sure they are safe. Some will undergo the last phase (P3) of human clinical trial this July. I think some have already advanced the manufacturing production of vaccine but of limited quantity (millions) to limit losses if vaccine is ineffective. But if successful, they will start the mass (billions) production ready for public consumption.
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